• Cirrhosis
• Inflamatory Bowel Disease
• Sports Medicine

Awards

• Presidential Research Award - National Research council, Colombo 2013, 2012, 2010, 2006, 2001
• Vice Chancellors Award for the most outstanding researcher in Medicine 2010, 2014
• Poster of distinction APSL 2011
• Oral free paper prize for Best presentation in the Spotlight Session on Risk factors for non-acoholic fatty liver disease at UEG Week Vienna – October 2016
• Kumaradas Rajasuriya Prize for the Best Paper in Tropical Medicine 2016 Sri Lanka Medical Association Annual Sessions, Colombo 2016
• S E Seneviratna Prize for research paper 2016 Sri Lanka Medical Association Annual Sessions, Colombo 2016
• Wijerama Award for best research paper 2010, Sri Lanka Medical Association Annual Sessions, Colombo 2010
• Wijerama Award for best research paper 2014, Sri Lanka Medical Association Annual Sessions, Colombo 2014
• Professor Rajasuriya Prize for research paper 2010, Sri Lanka Medical Association Annual Sessions, Colombo 2010
• Professor Rajasuriya Prize for research paper 2000, Sri Lanka Medical Association Annual Sessions, Colombo 2000
• Rajasuriya Oration Medal, Ceylon College of Physicians 2012
• EV Peiris Oration Medal, Ceylon College of Physicians 2009
• Sir Markus Fernando Oration Medal, Sri Lanka Medical Association 2008
• Sir Markus Fernando Oration Medal, Sri Lanka Medical Association 2003
• Poster of Distinction DDW 2002
• National Science Foundation Research Grant (2004)
• University of Kelaniya Research Grant (2008)

• Ceylon college of Physicians – Council Member (2002-2004)
• Student Councilor University of Kelaniya 2006- to date
• Sri Lanka University Games Medical Sub Committee member 2007
• Life Member: Sri Lanka Medical Council
• Member of Oxford Society
• Member of Green College (Oxford) Alumni 2001 to date
• North Colombo Medical College Alumini Asscociation 1993 to date
• Gastroenterological and Digestive Endoscopy Society of Sri Lanka: Secretary (2003-2007)
• Gastroenterological and Digestive Endoscopy Society of Sri Lanka Council Member 2008 to date
• Member of the American Gastroenterology Association (AGA) 2010-
• Member of the Board of Study in Dermatology Post Graduate Institute of Medicine 2009
• Committee Member of the Sri Lanka Sports Ministry Disciplinary Enquires Board (2007)

• Ceylon College of Physicians: Young Physicians Lecture “The Management of acute upper gastrointestinal haemorrhage” Colombo Feb2000 
• Ceylon College of Physicians: Recent Advances in Inflammatory Bowel Disease. Colombo 2002
• Sir Markus Fernando Oration: From bench to bedside –The role of TNF-a polymorphisms in inflammatory bowel disease Sri Lanka Medical Association Colombo 2003 
• International Inflammatory Bowel Disease (IBD) conference: Colombo Feb 2005
• Sri Lanka College of Haematologists: Aneamea in Liver Disease. Colombo August 2006
• College of General Practitioners of Sri Lanka: GORD. Colombo October 2007
• United Nation Development Programme (UNDP): Lecture on Child abuse. Embilipitiya. June 2008
• Sir Markus Fernando Oration: Colitis in Sri Lanka – From microscopic to macroscopic. Sri Lanka Medical Association. Colombo Nov 2008
• The first conference on Endobolism 2011 Xiemen China
• IBD in Asia. Ceylon Collage of Physicians annual academic sessions 2014. 5^th to 8^th October 2014
• 5th World Congress of Science and Medicine in Cricket March 2015
• Ceylon College of Physicians, Specialty update programme 2014

Resource Person in Seminars and Workshops

• Main Organizer MD part 1 MCQ course Ceylon College of Physicians 2004, 2005
• Main Organiser, International IBD conference , Gastroenterological and Digestive Endoscopy Society of Sri Lanka.  February 2006.
• Annual Meeting of Clinical Teachers -Medical Education Centre, Faculty of Medicine, University of Kelaniya. March 2006
• Sri Lanka Medical Association 39^th Annual Academic Sessions: Symposium-Gastroenterology – Chairperson. Colombo, September 2006
• Development of Best Practice guidelines in Histopathology reporting Consensus Meeting, College of Pathologists Sri Lanka, January 2007
• International conference on gastrointestinal pathology “ICON_GI 2007” September 2007
• Resource person Ceylon College of Physicians MCQ course for MD part I 2008 May 2008
• Ceylon College of Physicians and Galle Medical Association joint Sessions August 2008 Guide lines on management of Hepatic encephalopathy
• Resource person Kandy Society of Medicine Annual Academic Session February 2009. “Anaemia of gastrointestinal origin in the elderly”
• Resource person Ceylon College of Pathologist Annual Academic Sessions 2010. “The Management of IBD”

• Shaman Rajindrajith,Arunasalam Pathmeswaran,Chamilka Jayasinghe,Dulani Kottahachchi,Anuradhani Kasturiratne,Shamila T. de Silva,Madunil A. Niriella,Anuradha S. Dassanayake,Arjuna P. de Silva and H. Janaka de Silva. Non-alcoholic fatty liver disease and its associations among adolescents in an urban, Sri Lankan community BMC Gastroenterology 201717:135
• Niriella MA, Kobbegala VJ, Karalliyadda HN, Ranawaka CK, de Silva AP, Dassanayake AS, de Silva HJ. Sero-prevalence and vaccination status of hepatitis A and hepatitis B among adults with cirrhosis in Sri Lanka: a hospital based cohort study. BMC Res Notes. 2017 Jul 21;10(1):303.
• Gunathilaka ML, Niriella MA, Luke NV, Piyarathna CL, Siriwardena RC, De Silva AP, de Silva HJ. Possible gasoline-induced chronic liver injury due to occupational malpractice in a motor mechanic: a case report. J Med Case Rep. 2017 Jul 3;11(1):179.
• Niriella MA, Pathmeswaran A, De Silva ST, Kasturiratna A, Perera R, Subasinghe CE, Kodisinghe K, Piyaratna C, Rishikesawan V, Dassanayaka AS, De Silva AP, Wickramasinghe R, Takeuchi F, Kato N, de Silva HJ. Incidence and risk factors for non-alcoholic fatty liver disease: A 7-year follow-up study among urban, adult Sri Lankans. Liver Int. 2017 May 19. [Epub ahead of print]
• Piyarathna T A, Niriella M A, de Silva AP, de Silva H J.Duodenal xanthelasmata Ceylon Med J. 2016 Dec 30;61(4):191. doi: 10.4038/cmj.v61i4.8389.
• De Silva AP, Niriella MA, Nandamuni Y, Nanayakkara SD, Perera KR, Kodisinghe SK, Subasinghe KC, Pathmeswaran A, de Silva HJ. Effect of audio and visual distraction on patients undergoing colonoscopy: a randomized controlled study. Endosc Int Open. 2016 Nov;4(11):E1211-E1214.
• Niriella MA, Kodisinghe SK, De Silva AP, Hewavisenthi J, de Silva HJ. Intestinal tuberculosis masquerading as difficult to treat Crohn disease: a case report. BMC Res Notes. 2016 Aug 24;9(1):417. doi: 10.1186/s13104-016-2222-0.
• Amarasiri DL1, Pathmeswaran A, Dassanayake AS, de Silva AP, Adikari MD, Sanjeewa PA, Jayaratne A, de Silva HJ.The prevalence of upper respiratory symptoms in a cohort of adults presenting with symptoms of gastro-oesophageal reflux disease. Ceylon Med J. 2016 Jun;61(2):63-7. doi: 10.4038/cmj.v61i2.8301.
• Subasinghe SK, Nandamuni Y, Ranasinghe S, Niriella MA, Miththinda JK, Dassanayake A, de Silva AP, de Silva HJ Association between road accidents and low-grade hepatic encephalopathy among Sri Lankan drivers with cirrhosis: a prospective case control study. BMC Res Notes. 2016 Jun 13;9:303. doi: 10.1186/s13104-016-2106-3.
• Kumarasena RS, Niriella MA, Ranawaka CK, Miththinda JK, de Silva AP, Dassanayaka AS, de Silva HJ. Predicting acute liver failure in dengue infection. Ceylon Med J. 2016 Mar;61(1):35-6. doi: 10.4038/cmj.v61i1.8260
• Kasturiratne A, Akiyama K, Niriella MA, Takeuchi F, Isono M, Dassanayake AS, de Silva AP, Wickremasinghe RA, Kato N, de Silva HJ. Association of genetic variants with non-alcoholic fatty liver disease in an urban Sri Lankan community. Liver Int. 2015 Feb;35(2):676-9. doi: 10.1111/liv.12624. Epub 2014 Jul 10.
• Wijewantha H S, de Silva A P, Niriella M A, Wijesinghe N, Waraketiya P, Kumarasena R S, Dassanayake A S, , Hewawisenthi J de S , de Silva H J. Usefulness of Routine Terminal Ileoscopy and Biopsy during Colonoscopy in a Tropical Setting: A Retrospective Record-Based Study. Gastroenterology Research and Practice. 2014 (2014)
• Kasturiratne A, Mufeena MN, Mettananda KC, Fernandopulle N, Rajindrajith S, Waraketiya PR, Weerasinghe SK, Ranaweera A, Hewavisenthi SJ, de Silva AP, de Silva HJ. Incidence of inflammatory bowel disease in Gampaha district: details of the Sri Lankan component of the Asia-Pacific Crohn's and Colitis Epidemiology Study. Ceylon Med J. 2014 Mar;59(1):16-8
• Ranawaka CK, Miththinda JK, Senanayake SM, de Alwis WR, Mufeena MN, Niriella MA, Dassanayake AS, de Silva AP, Pathmeswaran A, de Silva HJ. Validation of the Sinhala version of the Chronic Liver Disease Questionnaire (CLDQ) for assessment of health related quality of life among Sri Lankan cirrhotics. Ceylon Med J. 2013 Dec; 58(4):156-62
• Senanayake SM1, Fernandopulle AN, Niriella MA, Wijesinghe NT, Ranaweera A, Mufeena MN, Pathmeswaran A, Nawarathne NM, de Silva AP, de Silva HJ. The long-term outcomes of a cohort of Sri Lankan patients with ulcerative colitis: a retrospective study at twonational referral centers and review of literature. Clin Exp Gastroenterol. 2013 Sep 20;6:195-200. doi: 10.2147/CEG.S49202. eCollection 2013
• Amarasiri WA1, Pathmeswaran A, de Silva AP, Dassanayake AS, Ranasinha CD, de Silva HJ. Gastric motility following ingestion of a solid meal in a cohort of adult asthmatics. J Neurogastroenterol Motil. 2013 Jul;19(3):355-65. doi: 10.5056/jnm.2013.19.3.355. Epub 2013 Jul 8
• De Silva AP, Liyanage IK, De Silva ST, Jayawardana MB, Liyanage CK, Karunathilake IM.Migration of Sri Lankan medical specialists. Hum Resour Health. 2013 May 21;11(1):21. doi: 10.1186/1478-4491-11-21.
• Senanayake SM, Niriella MA, Weerasinghe SK, Kasturiratne A, de Alwis JP, de Silva AP, Dassanayake AS, de Silva HJ. Survival of patients with alcoholic and cryptogenic cirrhosis without liver transplantation: a single center retrospective study. BMC Res Notes. 2012 Dec 2;5:663
• Amarasiri DL, Pathmeswaran A, Dassanayake AS, de Silva AP, Ranasinha CD, de Silva HJ. Esophageal motility, vagal function and gastroesophageal reflux in a cohort of adult asthmatics. BMC Gastroenterol. 2012 Oct 12;12:140
• Kasturiratne A, Weerasinghe S, Dassanayake AS, Rajindrajith S, de Silva AP,Kato N, Wickremasinghe AR, de Silva HJ. Influence of non-alcoholic fatty liver disease on the development of diabetes mellitus. J Gastroenterol Hepatol. 2013;28:142-7.
• De Silva AP, Nandasiri SD, Hewavisenthi J, Manamperi A, Ariyasinghe MP,Dassanayake AS, Jewell DP, de Silva HJ. Subclinical mucosal inflammation in diarrhea-predominant irritable bowel syndrome (IBS) in a tropical setting. Scand J Gastroenterol. 2012 Jun;47(6):619-24.
• De Silva AP, Kumarasena RS, Perera Keragala SD, Kalubowila U, Niriella M,Dassanayake AS, Pathmeswaran A, de Silva HJ. The prone 12 o'clock position reduces ileal intubation time during colonoscopy compared to the left lateral 6 o'clock (standard) position. BMC Gastroenterol. 2011 Aug 4;11:89.
• Dassanayake AS, Kasturiratne A, Niriella MA, Kalubovila U, Rajindrajith S, De Silva AP, Kato N, Wickremasinghe R, de Silva HJ. Prevalence of Acanthosis Nigricans in an urban population in Sri Lanka and its utility to detect metabolic syndrome. BMC Res Notes. 2011 Jan 28;4(1):25.
• De Silva AP, Niriella MA, Perera H, Aryasingha S, Kalubovila U, Manchanayake J, Dassanayake AS, Devanarayana NM, Pathmeswaran A, De Silva HJ. Is a six hour fast after a rice meal sufficient before upper gastrointestinal endoscopy? Scand J Gastroenterol. 2010 Mar 24.
• RS Kumarasena,M Nirella,U Kalubowilla, AP De Silva, AS Dassanayake,HJ de Silva Bleeding from oesophageal ulceration after variceal band ligation for primary prophylaxis for oesophageal varices. Gut accepted Sep 2010 ;59(11):1586.
• R S Kumarasena, S M Senanayake, K Sivaraman, AP de Silva, A S Dassanayake, R Premaratna ,B Wijesiriwardena, H J de Silva.Intravenous N-acytelcystine in dengue associated acute liver failure. Hepatol inter accepted 2010. 
• Niriella MA, De Silva AP, Dayaratne AH, Ariyasinghe MH, Navarathne MM, Peiris RS, Samarasekara DN, Satharasinghe RL, Rajindrajith S, Dassanayake AS, Wickramasinghe AR, de Silva HJ. Prevalence of inflammatory bowel disease in two districts of Sri Lanka: a hospital based survey. BMC Gastroenterol. 2010 Mar 19;10:32.
• de Silva AP, Karunanayake AL, Dissanayaka TG, Dassanayake AS, Duminda HK, Pathmeswaran A, Wickramasinghe AR, de Silva HJ. Osteoporosis in adult Sri Lankan inflammatory bowel disease patients. World J Gastroenterol. 2009 Jul 28;15(28):3528-31. 
• Amarasiri LD, Pathmeswaran A, De Silva AP, Dassanayake AS, Ranasinha CD, De Silva J. Comparison of a composite symptom score assessing both symptom frequency and severity with a score that assesses frequency alone: a preliminary study to develop a practical symptom score to detect gastro-oesophageal reflux disease in a resource-poor setting. Eur J Gastroenterol Hepatol. 2009 May 30.
• Dassanayake Anuradha S, Kasthuriratne Anuradhani, Rajindrajith Shaman, Kalubowila Udaya, Chakrawarthi Sureka, De Silva A P, Makaya Miyuki, Mizoue Tetsuya, Kato Norihiro, Wickremasinghe A Rajitha, de Silva H Janaka  Prevalence and risk factors for non alcoholic liver disease (NAFLD) in adults in an urban Sri Lanakan population. J Gastroenterol Hepatol 2009
• De Silva AP, Amarasiri L, Kottachichi M, Dassanayake A, De Silva HJ. A one hour fast for water and a six hour fast for solids provides good endoscopic vision and provides minimum patient discomfort. J Gastroenterol Hepatol 2009
• Mettananda , de Silva AP, de Silva HJ Acute systemic paraquat intoxication: survival without long term complications . Ceylon Med J. 2008; 53:136-7. 
• de Silva HJ, de Silva NR, de Silva AP, Jewell DP. Emergence of inflammatory bowel disease 'beyond the West': do prosperity and improved hygiene have a role? Trans R Soc Trop Med Hyg 2008;102:895-7.
• de Silva AP, Aryasingha S, Dassanayake AS, Hevavisenthi J, Ratnasena BG, de Silva HJ. Mènétrier's disease treated with gastrectomy. Ceylon Med J. 2008 Mar;53(1):22-3.PMID: 18590266 [PubMed - in process]
• de Silva AP, Kasturiratne A, Liyanage DL, Karunanayaka TK, de S Hewavisenthi SJ, Dassanayake AS, Farrell GC, de Silva HJ. Is past exposure to hepatitis A protective against progressive fibrosis in non-alcoholic fatty liver disease? Liver Int. 2008 Jan;28(1):147-9. No abstract available. PMID: 18173565 [PubMed - indexed for MEDLINE]
• de Silva HJ, Dassanayake AS, Manamperi A, de Silva AP. Treatment of lamivudine-resistant hepatitis B infection in post-renal transplant patients with adefovir dipivoxil: preliminary results. Transplant Proc. 2006 Nov;38(9):3118-20. PMID: 17112914 [PubMed - indexed for MEDLINE]
• Armuzzi A, Ahmad T, Ling KL, de Silva A, Cullen S, van Heel D, Orchard TR, Welsh KI, Marshall SE, Jewell DP. Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31. Gut. 2003 Aug;52(8):1133-9. PMID: 12865271 [PubMed - indexed for MEDLINE]
• Ahmad T, Armuzzi A, Bunce M, Mulcahy-Hawes K, Marshall SE, Orchard TR, Crawshaw J, Large O, de Silva A, Cook JT, Barnardo M, Cullen S, Welsh KI, Jewell DP. The molecular classification of the clinical manifestations of Crohn's disease. Gastroenterology. 2002 Apr;122(4):854-66. Erratum in: Gastroenterology. 2003 Jul;125(1):281. PMID: 11910336 [PubMed - indexed for MEDLINE]
• van Heel DA, Udalova IA, De Silva AP, McGovern DP, Kinouchi Y, Hull J, Lench NJ, Cardon LR, Carey AH, Jewell DP, Kwiatkowski D. Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. Hum Mol Genet. 2002 May 15;11(11):1281-9. PMID: 12019209 [PubMed - indexed for MEDLINE]
• Ganeshwaran Y, Seneviratne SM, Jayamaha R, De Silva AP, Balasuriya WK. Dengue fever associated with a haematoma of the rectus abdominis muscle. Ceylon Med J. 2001 Sep;46(3):105-6. Review. PMID: 11732298 [PubMed - indexed for MEDLINE]
• Seneviratne SM, Ganeshwaran Y, Jayamaha R, De Silva AP, Balasuriya WK. A man with thyrotoxicosis, lymphoma and thymic hyperplasia. Ceylon Med J. 2001 Sep;46(3):102-3. PMID: 11732296 [PubMed - indexed for MEDLINE]
• Deen KI, de Silva AP, Jayakody M, de Silva HJ. Saphenoperitoneal anastomosis for resistant ascites in patients with cirrhosis. Am J Surg. 2001 Feb;181(2):145-8. PMID: 11425056 [PubMed - indexed for MEDLINE]
• de Silva AP, Seneviratne SL, Gunatilake SB, Fonseka M, Jayasekera R, de Silva A family with alkaptonuria showing quasidominant inheritance. Ceylon Med J. 1999 Sep;44(3):130-2. No abstract available. PMID: 10675999 [PubMed - indexed for MEDLINE]
• Gunatilake SB, de Silva AP, Jayamanne SF, de Silva HJ. Two cases of Creutzfeldt-Jakob disease. Ceylon Med J. 1998 Dec;43(4):246-7. No abstract available. PMID: 10355185 [PubMed - indexed for MEDLINE]
• de Silva AP, Molagoda A, Fernando PL, de Silva HJ. The young woman who could not stop vomiting. Postgrad Med J. 1998 Nov;74(877):691-2. No abstract available. PMID: 10197201 [PubMed - indexed for MEDLINE]
• de Silva AP, Premaratne R, Gunatilake SB, Fonseka MM, de Silva HJ. Red (wo)man syndrome. Ceylon Med J. 1998 Mar;43(1):33. No abstract available. PMID: 9624841 [PubMed - indexed for MEDLINE]