Professor P Shiromi Perera
BSc (C'bo), M.Phil (J'pura), PhD(Kel'ya)
Professor
Department of Biochemistry and Clinical Chemistry
Department of Biochemistry and Clinical Chemistry
Research Interests
- Hemoglobinopathies
- Red cell enzymopathies and membranopathies
- Anemia
Awards and fellowships
- ICMR short term Fellowship INDO/FRC/5O2/ D-1/2017-18- lHD (2017) Indian Council of Medical Research, New Delhi, India
- CICS short term Fellowship DO/CICS/552/2017 (2017) Centre for International Co-operation in Science, Chennai, India
- ICGEB short term Fellowship F/SRL11-01, (2011) International Centre for Genetic Engineering & Biotechnology, Italy
- ICGEB short term Fellowship F/SRL12-01, (2012) International Centre for Genetic Engineering & Biotechnology, Trieste, Italy
- EMBO short term Fellowship ASTF 414 – 2012 (2012) European Molecular Biology Organization, Heidelberg, Germany
- Senate Honours for Research Publications (2014) University of Kelaniya Sri Lanka
- Senate Honours for Research Publications (2015) University of Kelaniya Sri Lanka
Publications
Publications in Peer Reviewed Journals:
- Perera S, Bonsall D, Niriella M A, Allen A, Peries A C, Nelumdeniya U B, Dissanayake R, Silva I, de Cesare M, Klenerman P, Weatherall D J, Roberts D J, Premawardhena A P. Transfusion-transmitted hepatitis C: A cluster of cases in transfusion-dependent thalassaemia patients in Sri Lanka. Transfusion Medicine. 2020, 30, (5), 377-383.
- Perera S, Allen A, Silva I. et al. Genotype-phenotype association analysis identifies the role of α globin genes in modulating disease severity of β thalassaemia intermedia in Sri Lanka. Sci Rep 2019; 9, 10116.
- Allen A, Perera S, Perera L, Rodrigo R, Mettananda S, Matope A, Silva I, Hameed N, Fisher CA, Olivieri N, Weatherall DJ, Allen S and Premawardhena A, A “One-Stop” Screening Protocol for Haemoglobinopathy Traits and Iron Deficiency in Sri Lanka. Front. Mol. Biosci. 2019; 6:66.
- Perera PS, Allen A, Silva DPSI, Hapugoda M, Wickramarathne MN, Wijesiriwardena I, Efremov DG, Allen S, Rees D, Fisher CA, Weatherall DJ and Premawardhena, Genotype-phenotype associations in β thalassaemia Intermedia in Sri Lanka: the role of α globin genes in modulating disease severity (Submitted for Nature Scientific Report, November 2018).
- Premawardhena, A.; Perera P. S. Anaemia in Sri Lanka: the missing pieces. Ceylon Medical Journal 2018; 63(3): 105-107.
- Perera PS, Premawardhena A. Anaemia in the community: do we know enough? 2018. Section A E Newsletter , Sri Lanka Association of Advancement of Science ( submitted)
- Szlavicz, E., Perera, P.S., Tomboly, C., Helyes, Z., Zador, F., Benyhe, S., Borsodi, A., Bojnik, E., Further Characterization of Hemopressin Peptide Fragments in the Opioid and Cannabinoid Systems. Anesthesia and Analgesia 2015; 121(6):1488-94.
- Perera, P. S., Silva, I., Hapugoda, M., Wickramarathne, M. N., Wijesiriwardena, I., Efremov, D. G., Fisher, C. A., Weatherall, D. J., Premawardhena, A., Rare hemoglobin variants: Hb G-Szuhu (HBB: c.243CG), Hb G-Coushatta (HBB: c.68AC) and Hb Mizuho (HBB:c.206TC) in Sri Lankan families. Hemoglobin 2015; 39(1): 62-5.
- Pinidiyapathirage, M. J., Kasturiratne, A., Ranawaka, U. K., Gunasekara, D., Wijekoon, N., Medagoda, K., Perera, S., Takeuchi, F., Kato, N., Warnakulasuriya, T., Wickremasinghe, A. R., The Burden of diabetes mellitus and impaired fasting glucose in an urban population of Sri Lanka. Diabetic Medicine 2013; 30(3): 326-32.
- Perera PS, Jansz ER, Peiris H. Studies on neurotoxic effect of palmyrah flour,Vidyodaya Journal of Science, Sri Lanka. 2006; 13, 17-22.
- Perera PS, Deraniyagala SA, Ratnasooriya WD. Effect of water extracts of Ficus benghalensis on nociception and sedation in rats, Vidyodaya Journal of Science, Sri Lanka. 2002; 11, 1-10.
- Perera PS, Jansz ER and Peiris, H. Studies on amines of Amblygaster sirm. Are they causing for allergic reactions in Ambligaster sirm? Vidyodaya Journal of Science, Sri Lanka. 2002; 11, 87-97.
- Perera, PS, Silva, DP. S. I., Hapugoda, M., Wickramarathne, M. N., Wijesiriwardena, I, Efremov, D. G., Fisher, C. A., Weatherall, D. J. and Premawardhena, A. 2017. Increased Hb F in Beta Thalassaemia Intermedia patients in Sri Lanka associated with Extended Alpha Globin Genes, Thalassaemia International Federation World Congress 2017. pp 39.
- Perera, PS, Silva, DP. S. I., Hapugoda, M., Wickramarathne, M. N., Wijesiriwardena, I, Efremov, D. G., Fisher, C. A., Weatherall, D. J. and Premawardhena, A. 2015. Correlation of Genotype with Phenotype in β Thalassaemia Intermedia in Sri Lanka. 2nd PAN Asian Conference on Haemoglobinopathies. pp 101
- Perera, PS, Silva, DP. S. I., Hapugoda, M., Wickramarathne, M. N., Wijesiriwardena, I, Efremov, D. G., Fisher, C. A., Weatherall, D. J. and Premawardhena, A. 2013 Molecular Analysis of β Thalassaemia intermedia in Sri Lanka. 13th International Conference on Thalassaemia and Haemoglobinopathies. Thalassaemia International Federation World Congress 2013. pp 128
- De Silva ST, Perera PS, Anuruddhika HWD, Dissanayake R and Niriella MN. Hepatitis B and C virus infections among patients with chronic kidney disease from two presumed high-risk centers. 130th Annual Scientific Sessions of the SLMA 2018. pp 71.
- Perera PS, Silva DPSI, Hapugoda M, Wickramarathne MN, Wijesiriwardena I, Efremov DG, Fisher CA, Weatherall DJ and Premawardhena A. Clinical and molecular heterogeneity among beta thalassaemia intermedia in Sri Lanka. 128th Annual Scientific Sessions of the SLMA 2015. pp 145
- Perera PS, Niriella MA, Peries MA, Nelumdeniya UB, Dissanayake DMR, de Silva, DSl, de Silva HJ, Premawardhena. HCV and HBV infection among a cohort of Sri Lankan thalassaemic patients. 128th Annual Scientific Sessions of the SLMA 2015. pp 116-117.
- Perera PS, Silva DPSI, Hapugoda M, Wickramarathne MN, Wijesiriwardena I, Efremov DG, Fisher CA, Weatherall DJ and Premawardhena A. Characterization of beta globin mutation in Sri Lankan patients with beta thalassaemia intermedia. 126th Annual Scientific Sessions of the SLMA. 2013. pp 101
- Pinidiyapathirage MJ, Chakrewarthy S, Perera PS, Wijayasinghe YS, Williams S, Williams SS, Kato N and Wickremasinghe AR. Cardiovascular risk profile of the estate population of Sri Lanka. Ceylon Medical Journal, 2010; 55(Supplement 1): 38
- Pinidiyapathirage M, Warnakulasuriya T, Kasturiratne A, Ranawaka U, Gunasekera D, Wijekoon N, Medagoda K, Perera S, Takeuchi F, Kato N and Wickremasinghe A. Comparison of Urban Diabetics with Optimal and Suboptimal Control. Journal of Epidemiological Community Health. 2011;65 (Supplement 1): 312
- Sajiwanie JWA, Perera PS. Study and Comparison of nutritional values of some Sri Lankan traditional rice varieties, Proceedings of 65th Annual Sessions Sri Lanaka Association for the Advancement of Science. 2009; 218
- Perera PS, Jansz ER, Peiris H. Isolation of histamine producing bacteria from Amblygaster sirm fish., Tenth Anniversary International Symposium, Sabaragamuwa University of Sri Lanka. 2005; 82.
- Perera PS, Jansz ER, Peiris H. Studies on neurotoxic amines in Plamyrah flour. Tenth Anniversary International Symposium, Sabaragamuwa University of Sri Lanka. 2005; 75.
- Perera PS, Jansz ER and Peiris H. Studies on tyramine and histamine in Amblygaster sirm (spotted sardinella fish, Research Session, Faculty of Graduate Studies University of Sri Jayewardenepura, Sri Lanka. 2002; 43.
- Perera PS, Deraniyagala SA, Ratnesooriya WD. Effects of water extract of Fics benghalensis on nociception and sedation in rats, Proceedings of the twenty first annual Sessions of the Institute of Biology, Sri Lanka. 2001; 33.
Professional Contributions
Positions held and holding in academic and scientific bodies
- Member, Kelaniya medical faculty teachers association (September 2008- to date)
- Assistant Treasurer, Kelaniya Medical School Alumni Association since 2015
- Member, Senate, University of Kelaniya, June 2018 to date
- Member, Head meeting, University of Kelaniya, June 2018 to date
- Member, Faculty board, Faculty of Medicine, University of Kelaniya since 2008
- Member, Management committee, Faculty of Medicine since June 2018
- Member Quality Assurance committee, Faculty of Medicine since 2018 onwards
- Member, Curriculum committee, Faculty of Medicine, University of Kelaniya 2009-2010 and 2016- to date
- Member, Green practice committee, Faculty of Medicine, University of Kelaniya since January 2016
- Member, Ethics committee, Faculty of Medicine, University of Kelaniya August 2010 to January 2011
- Member, Welfare committee, Faculty of Medicine, University of Kelaniya since February 2016
- Member, Progress review committee, Faculty of Medicine, University of Kelaniya since February 2016
- Treasurer, exhibition organizing committee of the 25th anniversary medical exhibition, Faculty of Medicine, University of Kelaniya in 2016
- Chairperson, Finance sub-committee, of the 25th anniversary medical exhibition, Faculty of Medicine, University of Kelaniya in 2016
Medical Faculty Responsibilities
- Academic Warden, Girls hostel, Faculty of Medicine, since 2016
- Student advisor to undergraduate medical students, Faculty of Medicine since 2008
- Student counsellor, Faculty of Medicine, University of Kelaniya 2013/2014
Ongoing research
- Comprehensive biochemical and molecular analysis of patients suspected with inherited haemolytic anaemia in Sri Lanka and assessment of its contribution to anaemia burden in the community” (Principal investigator)
- Methemoglobinemia and oxidative stress according to clinical phenotype in the β thalassaemia in Sri Lanka (Co-investigators)
- A pilot study to evaluate zinc protoporphyrin and the dichlorophenolindophenol and one tube osmotic fragility tests to identify iron deficiency and carriers of either haemoglobin E or thalassaemia in Gampaha district, Sri Lanka (Co-investigator)
- Comparative analysis of Vitamin D status of β thalassemia patients in Sri Lanka; its impact on bone metabolism
- Level of awareness in ergonomics among sedentary office workers in Seethawaka division
Contact Details
Department
Bio-Chemistry & Clinical Chemistry
Bio-Chemistry & Clinical Chemistry
Tel
+94 11 2961130 (Office)
+94 11 2961131(Office)
+94 71 8074736 (Mobile)
+94 11 2961130 (Office)
+94 11 2961131(Office)
+94 71 8074736 (Mobile)
Email
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