Professor Y I Nilmini S Gunawardene
B.Sc(First class Honors), M.Sc in Biochemistry, Molecular Biology & Gene Technology, Ph.D in Molecular Endocrinology (Hong Kong)
Senior Professor
Molecular Medicine Unit
Molecular Medicine Unit
Specialization
Moloecular biology, Recombinant Gene Technology,Medical Entomology, Molecular Biology, Molecular Medicine
Research Interests
- Investigator of Dengu virus serotypes and genetic variability Effect of silent transmision and clustering of casses on transmision of Dengu Transmision of Filariasis in selected areas of Sri Lanka
Publications
Publications in Peer Reviewed Journals
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Perumal, A. N. I., Y. I. N. S. Gunawardene, and R. S. Dassanayake. "Setaria digitata in advancing our knowledge of human lymphatic filariasis. Journal of Helminthology: 1-10.(2015).
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Voronin, Denis, A. M. L. L. Abeykoon, YI Silva Gunawardene, and Ranil S. Dassanayake. "Absence of Wolbachia endobacteria in Sri Lankan isolates of the nematode parasite of animals Setaria digitata."Veterinary Parasitology (2014).
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Rodrigo, W. W., R. S. Dassanayake, S. J. Weerasena, and Y. I. Silva Gunawardene.Novel parasitic nematode-specific protein of bovine filarial parasite Setaria digitata displays conserved gene structure and ubiquitous expression."Tropical Biomedicine 31, no. 3 (2014): 514-524.
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Rodrigo WW, Dassanayake RS, Karunanayake EH, Gunawardene YINS, Weerasena OV. Heterologous expression, chaperone mediated solubilization and purification of parasitic nematode-specific growth factor-like protein of Setaria digitata. Asian Pacific Journal of Tropical Medicine 2014; 7(2): 85-92.
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Dassanayake RS, Mahadevan K, Gunawardene YINS. Development of single-strand conformational polymorphism to screen for mutations in hotspot regions of beta-globin gene of beta-thalassemia patients of Sri Lanka. The Southeast Asian Journal of Tropical Medicine and Public Health 2013; 44(1): 114-23.
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Wijegunawardana ND, Gunawardene YINS, Manamperi A, Senarathne H, Abeyewickreme W. Geographic information system (GIS) mapping of lymphatic filariasis endemic areas of Gampaha District, Sri Lanka based on epidemiological and entomological screening. The Southeast Asian Journal of Tropical Medicine and Public Health 2012; 43(3): 557-66.
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Manamperi A, Gunawardene NS, Wellawatta C, Abeyewickreme W, de Silva HJ. Hepatitis B virus (HBV) genotypes in a group of Sri Lankan patients with chronic infection. Tropical Biomedicine 2011; 28(2): 320-24.
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Manamperi A, Nugawela P, Gunawardene NS, AbeyewickremeW, de Silva HJ. RNA positive rates among anti-HCV reactive blood donors in Sri Lanka: A preliminary study. Indian Journal of Medical Microbiology 2010; 28(3): 264-65.
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Manamperi A, Hapuarachchi C, Gunawardene NS, Bandara A, Dayanath D, Abeyewickreme, W. STR polymorphisms in Sri Lanka: evaluation of forensic utility in identification of individuals and parentage testing. The Ceylon Medical Journal 2009; 54(3): 85-89.
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Dassanayake RS, Gunawardene YINS, Tobe SS. Evolutionary selective trends of insect/mosquito antimicrobial defensin peptides containing cysteine-stabilized alpha/beta motifs. Peptides 2007; 28(1): 62-75.
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Gunawardene YINS, Bendena WG, Tobe SS, Chan SM. Comparative immunohistochemistry and cellular distribution of farnesoic acid o-methyltransferase in the shrimp and the crayfish. Peptides 2003; 24(10): 1591-97.
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Gu PL, Gunawardene YINS, Chow BC, He JG, Chan SM. Characterization of a novel cellular retinoic acid/retinol binding protein from shrimp: expression of the recombinant protein for immunohistochemical detection and binding assay. Gene 2002; 288(1-2): 77-84.
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Gunawardene YINS, Tobe SS, Bendena WG, Chow BK, Yagi KJ, Chan SM. Function and cellular localization of farnesoic acid o-methyltransferase (FAMeT) in the shrimp, Metapenaeus ensis . European Journal of Biochemistry 2002; 269(14): 3587-95.
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GunawardeneYINS, Chow BK, He JG, Chan SM. The Shrimp FAMeT cDNA is encoded for a putative enzyme involved in the methyl farnesoate (MF) biosynthetic pathway and is temporally expressed in the eyestalk of different sexes. Insect Biochemistry and Molecular Biology 2001; 31(11): 1115-24: [Eratum in 32(2) pp239].
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Gunawardene YINS, Wijesundera WS, Karunanayake EH, Chandrasekharan NV, Jayasekara N, Siridewa K.A Simple and rapid non-radioactive oligonucleotide based hybridization assay for the detection of Wuchereria bancrofti. Southeast Asian Journal of Tropical Medicine and Public Health 1999; 30(2): 350-355.