Dr. Wasanthi Subasinghe

Dr C Wasanthi Subasinghe

BSc (Hon)(C'bo), Ph.D (Mich'State). Post Doctoral Fellow (John D.Dingell VA Medical Center,MI,USA)

Senior Lecturer (Grade I)
Department of Biochemistry and Clinical Chemistry

Specialization

Bio-Analytical Chemistry, Microfluidics

Research Interests

Awards and fellowships

Publications

Scientific Communications—Chapters in Books

Sustainability Commitment of the University of Kelaniya, Sri Lanka: recollection from 2014 to 2023, Subasinghe, W.*, wickramasingha, B., Epa, U., Springer- Nature Green Metrics in Higher Education- Measuring and Reporting on Sustainability Initiatives at Higher Education Institutions (Hardcover ISBN 978-3-032-00360-7, (eBook ISBN 978-3-032-00361-4) – In Press Due: 07 October 2025)
“හැදෙමු වැඩෙමු සුවෙන් සිටිමු” (ISBN: 978-624-5507-10-8).
Contribution: chapter themed “වෙනස් වෙමු, වෙනස් කරමු, පරිසර හිතකාමී වෙමු”
Manual for Safe Handling and Disposal of Laboratory Chemicals and Hazardous Waste, University of Kelaniya (ISBN 978-955-704-083-7)
Revision of Standard Operating Procedures Version 4.0, Ethics Review Committee, Faculty of Medicine, University of Kelaniya

Scientific Communications - Peer review full papers in indexed journals

Wickramasingha, W. S. B., Perera, W. W. A. M. R., Kodithuwakku, K. C., De Silva, K. V. N. T., Karunarathne, D. M. S. D., Weerasinghe, V. P. A., & Subasinghe, W. (2025). Assessment of level of public knowledge, attitude, and perception towards sustainable mangrove forest conservation: a case study from Negombo, Sri Lanka. Ocean & Coastal Management, 270, 107886. http://dx.doi.org/10.2139/ssrn.4757062
Wickramasingha, B., Nazeer, F., Nandasena, T., Nasara, F., Nayanananda, U., Nuwantha, S., ... & Subasinghe, W. (2025). Promoting sustainability in E-waste management: a comparison of household practices and awareness between STEM and non-STEM university students in Sri Lanka. Journal of Material Cycles and Waste Management, 1-16. https://doi.org/10.1007/s10163-025-02316-2
Indunil, G. M., Kumari, T. M. C. P., & Subasinghe, C. W. (2023, July). Infrastructure, curriculum delivery and service provision improvements made by the University of Kelaniya, Sri Lanka in transforming education towards sustainability in the midst of economic crisis, in post-covid 19 pandemic period. In IOP Conference Series: Earth and Environmental Science (Vol. 1194, No. 1, p. 012028). IOP Publishing. https://doi1088/1755-1315/1194/1/012028
Shinsugi, C., Gunasekara, D., Gunawardena, N. K., Subasinghe, W., Miyoshi, M., Kaneko, S., & Takimoto, H. (2019). Double burden of maternal and child malnutrition and socioeconomic status in urban Sri Lanka. PloS one, 14(10), e0224222. https://doi.org/10.1371/journal.pone.0224222
Karbwang, J., Koonrungsesomboon, N., Torres, C. E., Jimenez, E. B., Kaur, G., Mathur, R., ... & FERCAP Multi-Country Research Team. (2018). What information and the extent of information research participants need in informed consent forms: a multi-country survey. BMC medical ethics, 19(1), 79., https://doi.org/10.1186/s12910-018-0318-x
Jayaram, B., Syed, I., Singh, A., Subasinghe, W., Kyathanahalli, C. N., & Kowluru, A. (2011). Isoprenylcysteine carboxyl methyltransferase facilitates glucose-induced Rac1 activation, ROS generation and insulin secretion in INS 832/13 β-cells.Islets, 3(2), 48-57. https://doi.org/10.4161/isl.3.2.15016
Subasinghe, W., Syed, I., & Kowluru, A. (2011). Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 300(1), R12-R20. https://doi.org/10.1152/ajpregu.00421.2010
Syed, I., Jayaram, B., Subasinghe, W., & Kowluru, A. (2010). Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic β-cells.Biochemical pharmacology, 80(6), 874-883. https://doi.org/10.1016/j.bcp.2010.05.006
Meyer, J. A., Subasinghe, W., Sima, A. A., Keltner, Z., Reid, G. E., Daleke, D., & Spence, D. M. (2009). Zinc-activated C-peptide resistance to the type 2 diabetic erythrocyte is associated with hyperglycemia-induced phosphatidylserine externalization and reversed by metformin. Molecular BioSystems, 5(10), 1157-1162. https://doi.org/10.1039/B908241G
Tolan, N. V., Genes, L. I., Subasinghe, W., Raththagala, M., & Spence, D. M. (2009). Personalized metabolic assessment of erythrocytes using microfluidic delivery to an array of luminescent wells. Analytical chemistry, 81(8), 3102-3108. https://doi:10.1021/ac900084g.
Subasinghe, W., & Spence, D. M. (2008). Simultaneous determination of cell aging and ATP release from erythrocytes and its implications in type 2 diabetes. Analytica chimica acta, 618(2), 227-233. https://doi.org/10.1016/j.aca.2008.04.061
Carroll, J., Raththagala, M., Subasinghe, W., Baguzis, S., Oblak, T. D. A., Root, P., & Spence, D. (2006). An altered oxidant defense system in red blood cells affects their ability to release nitric oxide-stimulating ATP. Molecular BioSystems, 2(6-7), 305-311. DOI: 10.1039/B604362N

Scientific Communications – Conference Papers

15^th August 2025, Young Researchers Symposium, Faculty of Medicine, University of Kelaniya, “The Impact of the Economic Crisis on Advanced Level Students in Gampaha District, Sri Lanka: School Attendance, Access to Resources, and Academic Performance.”Aberathna T W N D¹, Abeydeera A. A. R. N., Abeysekera D. A. T., Abeysinghe A. H. M. V. P., Abeywardena C. N., Absan U. M., Subasinghe C. W.
23^rd -26^th July 2025, The Sri Lanka Medical Association 138^th Anniversary International Medical Congress, Colombo, Sri Lanka, “Assessing the impact of social media on medical students in Sri Lanka.” Hana A.H.A., Gunawardana R.M.G.O., Gunathunga B.A.P.M., Hasni M.R.F., Hansika P.H., Gunawickrama N.K., Subasinghe C.W.
16^th -18^th August 2024, The Sri Lanka Medical Association 137^th Anniversary International Medical Congress, Colombo, Sri Lanka, “Challenges and experiences faced by parents of children with attention deficit hyperactivity disorder (ADHD); a qualitative study at Colombo North Teaching Hospital (CNTH) and ‘Ayati’ National Centre for Children with Disabilities.” Apsara Y. M.G., Asantha W.A.J.B., Atapattu K.T.G., Bandara R.L., Bandara W.M.S.H., Chandradasa M., Subasinghe C.W.
3^rd – 5^th May 2024, WONCA South Asia Region Conference 2024, Colombo, Sri Lanka, “Knowledge and Attitudes on Organ Donation: Comparison between Medically Educated Undergraduate and Nonmedical Undergraduates Attending the University of Kelaniya, Sri Lanka.” Thilanjaya E. A. A., Udukala U. D. V. I., Walisinghe W. M. P. H., Weerakoon A. W. G. A. I., Weerakoon P. S., Subasinghe C. W.
12^th December 2023, 79^th Annual Sessions of the Sri Lanka Association for the Advancement of Science, Colombo, Sri Lanka, “Health and environmental impacts of extensive unregulated agrochemical usage: An online public awareness survey”. H. P. Sandeepani, D.T.D. Warnakulasuriya, S. U. Bandara, C. W. Subasinghe
17^thMarch 2023, 1^st International Research Conference for Medical Undergraduates 2023, General Sir John Defence University, Sri Lanka, “Awareness on household e-waste management and environmental and health impact of improper e-waste disposal among undergraduates of University of Kelaniya, Sri Lanka”, Nazeer F. Z., Nandasena P. A. T. T., Nasra M. N. F., Nayanananda U. C., Nuwantha A. A. S., Nisansala E. D. L., Subasinghe C. W.
11th - 16th December 2022, 78^th Annual Sessions of the Sri Lanka Association for the Advancement of Science, Colombo, Sri Lanka, “Quantitative analysis of microplastics content in Sri Lankan Sea salts”, A.P.W Sulochana, C.W Subasinghe and K.M.T.D Gunasekera
11th - 16th December 2022, 78^th Annual Sessions of the Sri Lanka Association for the Advancement of Science, Colombo, Sri Lanka, “Investigation of Disease Presentation in Primary and Secondary Infection of Dengue in Three Clinical Settings from 2016-2019”. J.A.J.C. Jayarathne, G.K.D.L. Perera, Thusitha P. Muhandiramlage, K.A.D.C. Gunasekara, C.W. Subasinghe
28-29 September 2022, 8^th International (Virtual) Workshop on UI Green Metric World University Rankings (IWGM 2022), “Efforts of transforming education towards sustainability by the University of Kelaniya, Sri Lanka in the midst of economic crisis, in post-covid 19 pandemic period” G. M. Indunil, T.M.C.P.Kumari, C. W. Subasinghe https://www.youtube.com/watch?v=IfWS_WwzbZo
13-15 June 2022, Royal College of Obstetricians and Gynecologists world congress 2022 (RCOG World Congress 2022), London, UK, “Perceived barriers for child-adoption among selected subfertile Sri Lankan women: A qualitative study” Nadeeshan L.D.R., Liyadipita L.A.M.R.P.B., Kuruppu K.S.C., Kulathunga H.A.U.N., Manojith H.P.S., Sanyasi R., Godamunne P., Subasinghe C. W.
24-25 February 2022, 5^th Global Public Health Conference (GlobeHeal 2022), Vertual Platform,“Oxidative stress in chronic occupational exposure to petroleum hydrocarbons among petrol pump workers in Gampaha district, sri Lanka, Jayasinghe W. H. N. N., Warnakulasuriya D. T. D., Medagoda K., Subasinghe C. W.
28-31 October 2021, 30^th Anniversary Academic Sessions, Faculty of Medicine, University of Kelaniya, Sri Lanka, “Knowledge, attitudes and practices on the use of European Number System and International Numbering System for coding food additives, among medical students of the Faculty of Medicine, University of Kelaniya”, S. P. N. Ekanayake, E. M. J. C. Ekanayake, W. I. U. Fernando, D. G. H. N. Gamage, SomNath Gurung, Dr. C. W. Subasinghe
28-31 October 2021, 30^th Anniversary Academic Sessions, Faculty of Medicine, University of Kelaniya, Sri Lanka, “Awareness of Breast Cancer, Risk Factors and Self-Examination of Breast among Grade 13 Advanced Level Students in selected Girls’ Schools, Gampaha Educational Zone”, J. M. M. K. Jayalath, D. P. Hettiarachchi, M. C. Hettiarachchi, Jigme Kuenzang, M. T. D. Lakshan, M. R. Y. R. Viduranga and Dr. C. W. Subasinghe
11-12 September 2019, 12^th International Research Conference, General Sir John Kothalawala Defense University, Sri Lanka, “Morbidity pattern of patients presenting to the emergency treatment unit over a one-year period at a base hospital in the Western Province in Sri Lanka.” K. G. Kodikara, W. M. Rukshani, H. R. Samanthika, S. W. Vithana, Wasanthi Subasinghe and D. Gunathilake
5-7 April 2019, 5^th International Conference on Education (ICEDU 2019), Kuala Lumpur, Malaysia, “Study on self-assessment competence among grade 12 and 13 students of two schools in Gampaha district, Sri Lanka.” W. N. Sulani, K.H.S.M Silva, P.S.A.P. Somarathna, W.G. Supun, D. Sonam, Dr. Wasanthi Subasinghe, Prof. M.N. Chandratilake
7^th February 2019, International Medical Undergraduate Research Conference (IMURC 2019, Faculty of Medical Sciences, University of Sri Jayewardenepura, “Study on self-assessment competence among grade 12 and 13 students of two schools in Gampaha district, Sri Lanka.” W. N. Sulani, K.H.S.M Silva, P.S.A.P. Somarathna, W.G. Supun, D. Sonam, Dr. Wasanthi Subasinghe, Prof. M.N. Chandratilake
20-21 November 2017, 17^th FERCAP international conference, New Delhi, India. “A multi-country study of what information and to which extent of information in informed consent forms research participants would like to receive” FERCAP Multi-Country Research Team (India, Indonesia, Malaysia, Philippines, Sri Lanka, Taiwan, and Thailand) Juntra Karbwang, Nut Koonrungsesomboon, Cristina E. Torres, Edlyn B. Jimenez, Gurpreet Kaur, Roli Mathur, Eti N. Sholikhah, Chandanie Wanigatunge, Chih-Shung Wong, Kwanchanok Yimtae, Murnilina Abdul Malek, Liyana Ahamad Fouzi, Aisyah Ali, Beng Z. Chan, Madawa Chandratilake, Shoen C. Chiew, Melvyn Y. C. Chin, Manori Gamage, Irene Gitek, Mohammad Hakimi, Narwani Hussin, Mohd F. A. Jamil, Pavithra Janarsan, Madarina Julia, Suman Kanungo, Panduka Karunanayake, Sattian Kollanthavelu, Kian K. Kong, Bing-Ling Kueh, Ragini Kulkarni, Paul P. Kumaran, Ranjith Kumarasiri, Wei H. Lim, Xin J. Lim, Fatihah Mahmud, Jacinto B. V. Mantaring III, Siti M. Md Ali, Nurain Mohd Noor, Kopalasuntharam Muhunthan, Elanngovan Nagandran, Maisarah Noor, Kim H. Ooi, Jebananthy A. Pradeepan, Ahmad H. Sadewa, Nilakshi Samaranayake, Shalini Sri Ranganathan, Wasanthi Subasinghe, Sivasangari Subramaniam, Nadirah Sulaiman, Ju F. Tay, Leh H. Teng, Mei M. Tew, Thipaporn Tharavanij, Peter S. K. Tok, Jayanie Weeratna, Tri Wibawa, Renu Wickremasinghe, Phanthipha Wongwai, Subhash Yadav and FERCAP Multi-Country Research Team

July 14, 2016, National Conference on Green Practices (ncgp) 2016, Battaramulla, Sri Lanka. “Perception among medical students on current green practices implemented at the Faculty of Medicine, University of Kelaniya”, Kumarasingha K.D.B., Wanigasingha P.T., Gunasekara K.A.D.C., Gunathilaka P.A.D.H.N., SubasingheW.
March 13, 2015, Annual Conference, National Comprehensive Cancer Network, Hollywood, FL, USA. “Analysis of clinico-pathological presentation of breast cancer in Sri Lankan women: Single unit experience during two-year follow up”, Subasinghe T. U., Hilmi A. J., Atulugama N. S., Subasinghe W., Kobbegala V. J., Pitigalaarachchi P., Siddhisena P. K.A.
November 2013, 14^th Annual Research Symposium of the University of Kelaniya, Kelaniya, Sri Lanka. “The Validity of body mass index in predicting budy fat percentage”, Piyasena, W.B.A.I., Jayasena, R.S.S., Subasinghe, W., Gunasekara, K.A.D.C.
June 21, 2014, Annual Scientific Sessions of the Faculty of Critical Care, The Collage of Anaesthesiologists of Sri Lanka. “Acute Pancreatitis: a study on incidence, etiology and severity assessment”, Subasinghe T. U., Pitigalaarachchi P., Gunasiri W.R.J., Subasinghe C. W.
December 11^th -15^th, 2010, American Society of Cell Biology; 50^th Annual Meetings, Philadelphia, PA, USA. “Phagocytic NADPH-oxidase mediates cytokine-induced oxidative stress and mitochondrial dysfunction in pancreatic beta-cells: potential involvement of Rac1/tiam1 signaling cascade”, Subasinghe, W., Syed, I. and Kowluru, A.
December 11^th -15^th, 2010, American Society of Cell Biology; 50^th Annual Meetings, Philadelphia, PA, USA. “Is the α-subunit of prenyltransferase a substrate for proapoptotic caspase-3 in pancreatic beta-cells?”, Subasinghe, W., Syed, I., Singh, A. and Kowluru, A.
December 11^th -15^th, 2010, American Society of Cell Biology; 50^th Annual Meetings, Philadelphia, PA, USA. “A prenylated pertussis toxin- sensitive G-protein-mediates nutrient-induced generation of ROS in INS 832/13 cells and rat islets”, Syed, I., Subasinghe, W., Kyathanahalli, C. N. and Kowluru, A.
December 11^th -15^th, 2010, American Society of Cell Biology; 50^th Annual Meetings, Philadelphia, PA, USA. “Isoprenylcysteine carboxyl methyltransferase [ICMT] facilitates glucose-induced Rac1 activation, ROS generation and insulin secretion in pancreatic β-cells”, Singh, A., Syed, I., Subasinghe, W. and Kowluru, A.
September 2010, Annual Research Day, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA, “Phagocytic NADPH-oxidase mediates cytokine-induced oxidative stress and mitochondrial dysfunction in pancreatic beta-cells: potential involvement of Rac1/tiam1 signaling cascade”, Subasinghe, W., Syed I., Rodriguez Z. A. and Kowluru, A.
September 2010, Annual Research Day, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA “Isoprenylcysteine carboxyl methyltransferase [ICMT] regulates insulin secretion Via Rac1 activation and ROS generation in pancreatic β-cells”, Singh, A., Syed, I., Subasinghe, W. and Kowluru, A.
September 2010, Annual Research Day, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA, “Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and the onset of mitochondrial dysfunction in pancreatic β-cells”.Syed, I., Jayaram, B., Subasinghe, W., and Kowluru, A.
April 2010, John D Dingell VA Medical Center Poster Research Symposyum, Detroit, MI, USA “Phagocytic NADPH-oxidase mediates cytokine-induced oxidative stress and mitochondrial dysfunction in pancreatic beta-cells: potential involvement of Rac1/tiam1 signaling cascade”, Subasinghe, W., Syed, I., Rodriguez, Z. A. and Kowluru, A.
April 2010, John D Dingell VA Medical Center Poster Research Symposyum, Detroit, MI, USA “Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and the onset of mitochondrial dysfunction in pancreatic β-cells”.Syed, I., Jayaram, B., Subasinghe, W., and Kowluru, A.
September 2009, Annual Research Day, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA “Novel regulatory role of Rac 1 in the glucolipotoxicity of the islet beta cells.”, Syed I., Jayaram B., Koch B., Subasinghe W., Kowluru A.
September 2009, Annual Research Day, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA “Cytokines-induced mitochondrial dysfunction in pancreatic beta-cell involves the activation of phagocytic NADPH-Oxidase”, Subasinghe, W., Rodriguez, Z. A., Syed, I., Kamath, V. and Kowluru, A.
September 2008, Diabetic Neuropathy Study Group of the EASD NEURODIAB, Orvieto, Italy, “Zn activated C-peptide and the concept of C-peptide resistance in diabetes”, Spence, D., Meyer, J., Medawala, W. and Subasinghe, W.
April 2008, Student seminar, Analytical Chemistry division, Department of Chemistry, Michigan State University, East Lansing, MI, USA, “Quantitative determination of glucose-6-phosphate dehydrogenase and its potential in diabetic complications”, Subasinghe, W.
January 2008, Lab Automation, Palm Springs, CA, USA, “A new role for red blood cells in the onset of diabetic complications”, Subasinghe, W. and Spence, D.
October 2006, Student seminar, Analytical Chemistry division, Department of Chemistry, Wayne State University, Detroit, MI, USA, “Analytical Approach for Systems Biology”, Subasinghe, W.
9-13^th December, 2003, 59^th Annual Sessions of the Sri Lanka Association for the Advancement of Science, “Effect of steam volatile constituents of some tropical plant species on callosobruchus maculatus”, Subasinghe, W., Deraniyagala, S. and Paranagama, P. A.

News Paper/Magazines

“Beyond planting trees, what can we do to be more eco-friendly in everyday life?” Ceylon Today, Thursday 20^th October 2022, FOCUS A5

Reviewer/Editor for Journals

Editor, Sri Lanka Journal of Sustainable development Studies. Published by the Centre for Sustainability Solutions, University of Kelaniya. (July 2025 – to date)
Reviewer for The Journal of the National Science Foundation of Sri Lanka.
Reviewer for “GreenInsight” e-magazine (ISSN 2827-7333) Volume 3 published by the Centre for Sustainability Solutions, University of Kelaniya.
“GreenInsight” e-magazine (ISSN 2827-7333) Volume 2 published by the Centre for Sustainability Solutions, University of Kelaniya.
“GreenInsight” e-magazine (ISSN 2827-7333) Volume 1 published by the Centre for Sustainability Solutions, University of Kelaniya.

Professional Contributions

Ongoing research

<< Back to listing

Contact Details

Department
Bio-Chemistry & Clinical Chemistry

Tel
+94 112961131 (Office)

Email
This email address is being protected from spambots. You need JavaScript enabled to view it.

Dr C Wasanthi Subasinghe

Contact Details

Connect with us

Quick Links

Clinical Services

SUPPORT US

REACH US

Main Menu

Diploma

Dr C Wasanthi Subasinghe

Contact Details

Connect with us

Quick Links

Clinical Services

SUPPORT US

REACH US

Main Menu