Dr Padmapani Padeniya
MBBS(Pera), MSc in Clinical Genetics
Senior Lecturer (Grade II)
Department of Anatomy
Department of Anatomy
Specialization
Clinical Genetics
Research Interests
- Thalassaemia
- Reproductive Genetics
- Dysmorphology
Awards, Research grants and Scholarships
- The Poster of Distinction at DDW - Digestive Disease Week 2024 Conference of the paper “IS LIVER FAT CONTENT MORE IMPORTANT THAN LIVER IRON IN TRYING TO REVERSE LIVER FIBROSIS IN PATIENTS WITH TRANSFUSION-DEPENDENT BETA THALASSAEMIA? - A FOLLOW-UP STUDY” on May 18-21, 2024, at the Walter E. Washington Convention Center in Washington, D.C, USA.
- E M Wijerama Prize for the best oral paper at the 136th SLMA Anniversary International Medical Congress 2023, the paper “Assessing reversibility of liver fibrosis in patients with transfusion-dependent beta thalassaemia following intensive chelation” by Padeniya AGPM, Ediriweera D, Niriella MA, De Silva A, Premawardhena AP.
- The University of Kelaniya Senate honours for publishing in high-impact journals – 2022 and 2023.
- University Grant Commission Grant: Recipient of a research grant of Rs: 4.8 million (the maximum ceiling amount for a local candidate) for the research project on Evaluating Chronic Liver Disease due to iron overload in patients with beta thalassaemia major and assessing the reversibility of liver fibrosis with an aggressive chelation protocol.
- National Science Foundation Grant: A travel grant of Rs. 200,000/- to attend the 16th Human Genome Meeting, Sydney, Australia. March 11th -14th, 2012.
- Recipient of the scholarship awarded by Central Manchester University Hospital, Manchester, to attend the “Manchester Dysmorphology Course” from November 1st – 3rd, 2011
- September 2010 to August 2012, recipient of the NOMA scholarship to follow the MSc in Clinical Genetics funded by NORAD and managed by the Centre for International Co-operation in Higher Education, Oslo, Norway.
Invited speeches
- Participation as a Panel member for the Medicare 2024- National Healthcare Specialised Doctor’s Seminar Programme on the 2nd of March 2024 at the BMICH Colombo.
- Invited speaker and Resource person at the 46th Annual Academic Session of the Kandy Society of Medicine at the symposium on Obstetrics and Gynaecology, the lecture on “ Genetics in Obstetrics and Gynaecology” held on 9th of February 2024.
- Invited speaker and Resource person at the online crash course on Paediatric Liver Disease and Transplant and delivered a lecture on “The Role of Genetics in a Child with Liver Disease”, held on 24th April 2023.
- Invited speaker in the Symposium of “Genetics in perinatal care - the challenges in the pre-implantation genetic assessment” at the Perinatal Society of Sri Lanka Annual Conference held on 5th November 2022 at the Hotel Galadari Colombo.
- Invited speaker in the workshop on “Training on thalassaemia Screening, Diagnosis, and Counselling for Medical officers and Nursing officers in Thalassaemia Units” Organised by the NCD unit, Ministry of Health, held on 18th of August 2022, at Virtual online platform.
- Invited speaker in the symposium “Genetics in Obstetrics and Gynaecology” in the 53rd Annual Congress of the SLCOG on 15th – 18th October 2020 at the BMICH.
- Invited speaker at the SLMA Pre-Congress Virtual Workshop 2020 for the webinar on “Clinical Genomics for Medical Practitioners” held on Saturday, the 18th of July, 2020, at the SLMA.
- Invited speaker at the 4th Academic Sessions of the Post Graduate Institute of Medicine (PGIM), University of Colombo, Sri Lanka, held from 17th to 19th July 2013.
Publications
Book chapters
- Authored the following chapters in Histopathology course material (MDU4426) in the Bachelor of Medical Laboratory Sciences Honours Degree Programme of the Open University of Sri Lanka
- Histology of bone, cartilage, and muscles
- Histology of male and female reproductive systems
- Histology of reticuloendothelial system, lymphoid tissue, spleen, and lymph node
- Histology of liver
- Dissertation on ‘Genetic modifiers of Beta Thalassaemia: Phenotype Genotype Relationship in a Sri Lankan Population’ for the MSc in Clinical Genetics, at Faculty of Medicine, University of Colombo.
- Co-author of the booklet "What you should know about Haemophilia" - an information booklet in Sinhala published by the College of Haematologists in 2007.
Journal articles
- Padeniya P, Ediriweera D, De Silva AP, Niriella M, Premawardhena A. “The association between steatosis and liver damage in transfusion-dependent beta thalassaemia patients.” Br J Haematol. 2023 Feb;200(4):517-523. https://doi.org/10.1111/ bjh.18492
- Padmapani Padeniya, Dileepa Senajith Ediriweera, Arjuna P. De Silva, Madunil Anuk Niriella, Anuja Premawardhena “Using FIB-4 score as a screening tool in the assessment of significant liver fibrosis (F2) in patients with transfusion-dependent beta thalassaemia: a cross-sectional study” BMJ Open 2022;12:e061156. doi:10.1136/ bmjopen-2022-061156
- Padmapani Padeniya*, Hemali Goonasekara, Gayan Abeysekera, Rohan Jayasekara and Vajira Dissanayake. “Frequency of Hereditary Haemochromatosis Gene (HFE) variants in Sri Lankan transfusion-dependent beta thalassaemia patients and their association with the serum ferritin level,” Pediatr., 12 July 2022, https://doi.org/10.3389/fped.2022.890989
- Nirmani P Kaluarachchi, Malshani H Randunu, Munshifa Jainulabdeen, Arunthusha Thavarajah, Padmapani Padeniya, Prasanna Galhena. Case report of "Complex Y chromosomal anomalies in an infertile male," JBRA Assisted Reproduction 2020;00(0):000-000 : https://doi: 10.5935/1518-0557.20200022
- Padeniya, P., Siriwardana, S., Ediriweera, D. et al. Comparison of liver MRI R2(FerriScan®) VS liver MRI T2* as a measure of body iron load in a cohort of beta thalassaemia major patients. Orphanet J Rare Dis 15, 26 (2020). https://doi.org/10.1186/s13023-020-1301-4
- Padeniya, A. G. P. M., and T. D. Dias. "Invasive prenatal testing at a Tertiary Fetal Medicine referral center in Sri Lanka: A service evaluation audit." Sri Lanka Journal of Obstetrics and Gynaecology37, no. 1 (2015).
- Padeniya, Padmapani M., Imaya Godapitiya, Duminda R. Pathirana, Rohan W. Jayasekara, and Vajira HW Dissanayake. "A Sri Lankan Child with 48, XXXX Syndrome." The Indian Journal of Pediatrics 81, no. 2 (2014): 201-202. DOI 10.1007/s12098-013-0995-x
Oral presentations
- Oral presentation of the paper “Review of Clinical and whole exome sequencing results from patients with Developmental and Epileptic Encephalopathy with or without Drug Resistance (DEE +/- DRE) attending the National Epilepsy Centre of Sri Lanka” at the 17th annual congress of Association of Sri Lankan Neurologists 2024 from 1st- 4th March at the Cinnamon Grand Hotel Colombo.
- Oral presentation of the paper: “Pregnant Women’s Attitudes Towards Decision-Making and Implementing NIPT in National Antenatal Care in Sri Lanka” at the Perinatal Society of Sri Lanka on 5th - 6th September 2023 at the Hotel Cinnamon Grand, Colombo, Sri Lanka.
- Oral presentation of the paper “Assessing reversibility of liver fibrosis in patients with transfusion-dependent beta thalassaemia following intensive chelation therapy” at the 136th Anniversary International Medical Congress of the Sri Lanka Medical Association from 25th – 27th July 2023 at the BMICH.
- Oral presentation of the paper “Assessing liver fibrosis in patients with transfusion-dependent beta thalassaemia - a predictive model” at the 134th Anniversary International Virtual Medical Congress of the Sri Lanka Medical Association from 21st – 24th September 2021.
- Oral presentation of the paper “Comparison of screening results vs. pregnancy outcomes in patients screened using the non-invasive g-scan test (non-invasive prenatal testing)” at the 52nd Annual scientific congress of Sri Lanka College of Obstetricians and Gynaecologists from 11th – 12th August 2019 at Galadari Hotel, Colombo, Sri Lanka.
- Oral presentation of the paper “Hereditary breast cancer gene variants: multigene panel testing outcome from Sri Lanka“ at the 52nd Annual Scientific Congress of Sri Lanka College of Obstetricians and Gynaecologists from 11th – 12th August 2019 at Galadari Hotel, Colombo, Sri Lanka.
- SLCOG oral presentation of the paper “Surveillance of final outcome of in vitro fertilisation using pre-implantation genetic screening in Sri Lanka: An observational study“ at the 51st Annual Scientific Congress of Sri Lanka College of Obstetricians and Gynaecologists from 11th – 12th August 2018 at Sri Lanka Foundation, Colombo, Sri Lanka.
- SLMA oral presentation of the paper “Comparison of Liver MRI R2 (Ferriscan) vs MRI T2* as a measure of body iron load in a cohort of beta thalassaemia major patients“ at the 131st Anniversary International Medical Congress of the Sri Lanka Medical Association from 26th – 29th July 2018 at the Galadari Hotel, Colombo, Sri Lanka.
- Oral presentation of the paper “Pattern of fetal anomalies detected at the mid-trimester scan- Sri Lankan experience” at the SLCOG Golden Jubilee Conference in collaboration with FIGO, AOFOG, SAFOG from 3rd – 6th August 2017 at the BMICH, Colombo, Sri Lanka.
- Oral presentation of the paper “Proportion of genetic disorders detected at prenatal testing in a tertiary fetal medicine referral centre“ at the SLCOG Golden Jubilee Conference in collaboration with FIGO, AOFOG, SAFOG from 3rd – 6th August 2017 at the BMICH, Colombo, Sri Lanka.
- Oral presentation of the paper” Non-invasive prenatal testing outcomes in Tertiary Fetal Medicine Referral Centre in Sri Lanka” at the Annual Academic Sessions of the College of Obstetricians and Gynaecologists of Sri Lanka- July 2015.
- Oral presentation of the paper” Invasive prenatal testing outcome in a Tertiary Fetal Medicine referral centre in Sri Lanka” at the FIGO-SAFOG-SLCOG 2014 International conference from 31st October – 2nd November 2014 at the BMICH, Colombo, Sri Lanka.
- Oral presentation of the paper “A Retrospective comparison of the outcome of neonates of Meconium stained liquor(MSL) and clear liquor at birth” at the SLCOG secessions in 2013.
- Oral presentation of the paper “Neonatal outcomes of mothers with diabetes in pregnancy: retrospective and a comparative study” at the 12th Annual Scientific Secessions of the Perinatal Society of Sri Lanka on 2nd July 2013.
Poster Presentations
- E-Poster presentation of the paper “Knowledge and Attitudes Non-invasive Prenatal Testing (NIPT) in Sri Lankan Pregnant Mothers ” at the World Congress of Royal College of Obstetricians and Gynaecologists 2023
- Poster presentation of “Warfarin Embryopathy Despite Anticoagulation with Low Dose Warfarin and Bridging Therapy with Heparin: The First Reported Case from Sri Lanka” at the 25th Annual Scientific Congress of the Sri Lanka College of Paediatricians from 13th – 16th of May 2023.
- Poster presentation of “Clinical Profile of Children with Wilson Disease: Experience of a Tertiary Paediatric Liver Center” at the 25th Annual Scientific Congress of the Sri Lanka College of Paediatricians from 13th – 16th of May 2023.
- Poster presentation of the “Prenatal Genetic Screening for Sandhoff disease” case at the 3rd Annual Rare Disease Day Symposium- 2019 at the Lady Ridgeway Hospital, Borella, Colombo, Sri Lanka.
- Poster presentation of the paper “Hereditary breast cancer gene variants- multigene panel testing outcome from Sri Lanka” at the European Human Genetics conference from 16th – 19th June 2018, Milan, Italy.
- Poster presentation of the paper “Foetal Anomalies Detected in Sri Lankan Tertiary fetal medicine referral centre“ at the 27th World Congress on Ultrasound in Obstetrics and Gynaecology from 16th – 19th September 2017, Vienna, Austria. Published in SUPPL.1, Volume 50, September 2017 in the journal of ULTRASOUND in Obstetrics and Gynaecology.
- Poster presentation of the paper “The anatomical relationship of the parotid duct to the buccal and zygomatic branches of the facial nerve: a Sri Lankan study." Special supplement of the Ceylon Medical Journal, Volume 62, Supplement 1, July 2017.
- Poster presentation of the paper “Descriptive Study of Nuchal Translucency Scan Outcome in a Tertiary Fetal Medicine Referral Center in Sri Lanka” at the Human Genome Meeting Conference from 5th – 7th February 2017 in Barcelona, Spain.
- Poster presentation of the paper “Variations of Intra-Parotid Course of Facial Nerve” at the Asia Pacific International Conference of Anatomists from 17th – 20th March 2016.
- Poster presentation of the paper “Anatomical variations of the musculocutaneous nerve- A cadaveric study” at the 44th Annual Academic Sessions of the College of Surgeons of Sri Lanka- August 2015, Volume 33, Issue Supplement S1 ISSN 1391-491X.
- Poster presentation of the paper “Anatomical variations of the common peroneal nerve and the deep peroneal nerve in the lateral compartment of the leg- A cadaveric study” at the 44th Annual Academic Sessions of the College of Surgeons of Sri Lanka- August 2015, Volume 33, Issue Supplement S1 ISSN 1391-491X.
- Poster presentation of the paper “Haemochromatosis gene (HFE) in transfusion dependant thalassaemia: phenotype-genotype relationship in a Sri Lankan population” at the 127th Anniversary International Medical Congress of the Sri Lanka Medical Association, from 15th to 18th July 2014.
- Poster presentation of the paper “Genetic services provided at De Soysa Hospital for Women from September 2012 to March 2014 – Retrospective analysis” at the 127th Anniversary International Medical Congress of the Sri Lanka Medical Association, from 15th to 18th July 2014.
- Poster presentation of the paper “Pregnancy outcomes with meconium-stained liquor (MSL) at birth: retrospective comparison study” at the 127th Anniversary International Medical Congress of the Sri Lanka Medical Association, from 15th to 18th July 2014.
- Poster presentation of the paper “Descriptive study of Genetic services provided at De Soysa Hospital for Women from September 2012 to December 2013” at the International Conference on Birth Defects 2014 on 9th - 11th February at the Water’s Edge, Colombo, Sri Lanka.
- Poster presentation of the paper ”Genetic modifier of Hereditary Haemochromatosis gene (HFE) in transfusion dependant thalassaemia: phenotype-genotype relationship in a Sri Lankan population” at the Thalassaemia International Federation World Congress 2013 on 20th - 23rd of October in Abu Dhabi, UAE.
- Poster presentation of the paper “Meconeum stain liquor and the outcome of neonates: a retrospective study” at the 126th Anniversary Scientific Medical Congress of the Sri Lanka Medical Association, from 09th to 13th July 2013.
- Digital poster presentation of the paper “Risk factors for diabetes in pregnancy in South Asian women: a retrospective comparison” at the 22nd Malaysian International Congress of Obstetrics and Gynaecology on 30th May- 2nd June 2013.
- Digital poster presentation of the paper “Maternal and Neonatal Outcomes of Meconium-stained Liquor at Birth: A Descriptive Retrospective Study” at the 22nd Malaysian International Congress of Obstetrics and Gynaecology.
- Digital poster presentation of the paper “A Descriptive Study of Alpha and Beta Thalassaemia Mutations in Sri Lanka” at the Human Genome Meeting, Sydney, Australia. March 11th -14th, 2012.
Newspaper Articles and TV interviews
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High school education program to raise awareness of Thalassaemia: A Webinar on “Thalassaemia in Sri Lanka” Virtual Presentation and Discussion Session at Alethea International School, Sri Lanka on 19th of May 2022
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Ada Derana Twenty Four Sri Lanka’s News Channel under the “Jeevithayata Edak” program “ Are you aware of thalassemia” a TV interview on the 8th May 2022 at 3.30-4.00 pm in leu of World Thalassemia Day. https://youtu.be/hEb9FYvTlkc
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YouTube video “Thalassaemia free child for a couple with thalassemia carrier status” in lieu of the 30th-anniversary (2021) of the Faculty of Medicine, University of Kelaniya. https://www.youtube.com/watch?v=XKYtTSRQ2xM&t=13s
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National English Newspaper article on ‘Embryo Testing and Reproductive Genetics’ published in “The Morning” Sunday paper under the Health Column on 24th of January 2021.
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National English Newspaper article on ‘World Down syndrome Day 2021’ published in “The Morning” Sunday paper under the Health column on 21st of March 2021.https://epaper.themorning.lk/Home/MShareArticle?OrgId=2137fa9732c&imageview=0
Professional Contributions
- Member of the Ethics Committee, De Soyza Hospital for Women in Colombo from 2013 August to 2014 April.
- Member of Sri Lanka Medical Association
- Member of College of Dermatologists, Sri Lanka
- Conducted genetic awareness creation sessions island wide and have carried out sessions at all major hospitals including teaching hospitals of Karapitiya, Anuradhapura, Ragama, Peradeniya and Jaffna. This was organized by the Health Ministry of Sri Lanka in order to prevent the occurrence of genetic diseases and reduce birth defects in the community.
Contact Details
Department
Anatomy
Anatomy
Tel
+94 11 2958219 (Office)
+94 11 2958039 (Office)
+94 11 2956188 (Office)
+94 11 2632884 (Residence)
+94 11 2958219 (Office)
+94 11 2958039 (Office)
+94 11 2956188 (Office)
+94 11 2632884 (Residence)
Email
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