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01.2. Phase II

    i. Basic Epidemiology (Lectures - 12 hours + Tutorials - 4 hours)

Learning Objectives

Content

Activity

Time

Describe concepts of epidemiology

Definition of epidemiology

Epidemiologic approach

Descriptive epidemiology in terms of  time, place and person

History – Evolution of epidemiology

Uses of epidemiology

Natural history of disease

Lecture

1

Define, calculate and interpret measures of morbidity

Measurements in epidemiology: Rate, Proportion and Ratio

Measures of disease frequency:

Cumulative incidence, Special incidence rates:

Uses of incidence , Prevalence Rate:

Point prevalence/ Period prevalence

Relationship between incidence and prevalence

Uses of prevalence

Lecture

1

Define, calculate and interpret measures of mortality

Measures of mortality:

Crude death rate

Specific death rates: age, sex & cause

Proportionate Mortality

Proportionate Mortality Ratio

Lecture  

1

Describe different epidemiological study designs, uses and limitations

Classification of study designs

Descriptive studies, Case control studies

Cohort studies, Cross sectional studies

Lecture

2

Calculate and interpret measures of effect

OR, RR, AR, ARP, Mean difference

CI, 95% CI for effect measures

Interpretation / application of effect measures

Lecture

1

Describe and critically read a research paper on controlled trial

Experimental studies:

Difference between experimental and quarsi-experimental studies

Different types of exp. Study designs

Community trials/ Drug trials

Before and after designs,

Pararalled group designs

Phase I, II, III, and VI trials

Selection of experimental group

Selection of control group/s:

Application of simple randomization – advantages /disadvantages

Single / double blinding,Intention to treat analysis

Lecture

1

Describe a screening test

Screening criteria

Sensitivity, specificity, FPR, FNR, Predictive value

Likelihood ratio

Lecture

1

Describe factors considered to determine causation of disease

Causal criteria

Lecture

1

Describe quality of data

Selection bias, information bias and confounding bias

Reliability

Validity

Lecture

1

Describe “Evidence Based Medicine” (EBM)

Definition of EBM and EBPH. level of evidence,

Advantages of systematic review and Meta-analysis

Steps involved in designing a systematic review

Interpretation of a forest plot

Lecture

1

Explain the importance of qualitative research

Different between quantitative and qualitative research

Focus group discussions

In depth interviews

Lecture

1

 

RECOMMENDED READING MATERIAL

  • Jayawardana PL, Abeysena HTCS and Pathmeswaran A 2009, Hand book on Research Methodology for medical undergraduates, Faculty of Medicine, University of Kelaniya.

  • Sivagnanasundram C 1999, Learning Research, ISBN : 955-96654-0-5

  • Hennekens CH and Buring JE, Mayrent SL (Ed) 1987, Epidemiology in Medicine, Lippincott Williams and Wilkins, Tokyo.

  • Barker DJP and Hall AJ 1994, Practical Epidemiology, Churchill Livingston, Edinburgh.

  • Barker DJP, Cooper C and Rose G 1998, Epidemiology in Medical Practice, Churchill Livingston, Tokyo.

  • Last JM 2001, A Dictionary of Epidemiology, Oxford University Press, Oxford.

  • Park, K 2007, ‘Principles of Epidemiology and Epidemiologic Methods’, in Park’s Text Book of Preventive and Social Medicine pp. 48- 87, Banarsidas Bhanot Publishers, Jabalpur, India.

  • Park, K 2007, ‘Screening for Disease’, in Park’s Text Book of Preventive and Social Medicine pp. 115- 122, Banarsidas Bhanot Publishers, Jabalpur, India.

        

CONNECT WITH US

Department of Public Health,
Faculty of Medicine,
University of Kelaniya,
P.O Box 6,
Thalagolla Road,
Ragama,
Sri Lanka

  • Tel :  +94 11 2953411

  • Tel :  +94 11 2961140

  • Email:  publichealth@kln.ac.lk

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